HelixGAN a deep-learning methodology for conditional de novo design of α-helix structures

MOTIVATION: Protein and peptide engineering has become an essential field in biomedicine with therapeutics, diagnostics and synthetic biology applications. Helices are both abundant structural feature in proteins and comprise a major portion of bioactive peptides. Precise design of helices for bindi...

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Detalles Bibliográficos
Autores principales: Xie, Xuezhi, Valiente, Pedro A, Kim, Philip M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887083/
https://www.ncbi.nlm.nih.gov/pubmed/36651657
http://dx.doi.org/10.1093/bioinformatics/btad036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887083/
https://www.ncbi.nlm.nih.gov/pubmed/36651657
http://dx.doi.org/10.1093/bioinformatics/btad036

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