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HelixGAN a deep-learning methodology for conditional de novo design of α-helix structures
MOTIVATION: Protein and peptide engineering has become an essential field in biomedicine with therapeutics, diagnostics and synthetic biology applications. Helices are both abundant structural feature in proteins and comprise a major portion of bioactive peptides. Precise design of helices for bindi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887083/ https://www.ncbi.nlm.nih.gov/pubmed/36651657 http://dx.doi.org/10.1093/bioinformatics/btad036 |