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Local and Systemic Overexpression of COMP-Ang1 Induces Ang1/Tie2-Related Thrombocytopenia and SDF-1/CXCR4-Dependent Anemia

While supplemental angiopoietin-1 (Ang1) improves hematopoiesis, excessive Ang1 induces bone marrow (BM) impairment, hematopoietic stem cell (HSC) senescence, and erythropoietic defect. Here, we examined how excessive Ang1 disturbs hematopoiesis and explored whether hematopoietic defects were relate...

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Detalles Bibliográficos
Autores principales:	Sim, Hyun-Jaung, Bhattarai, Govinda, Kim, Min-Hye, So, Han-Sol, Poudel, Sher Bahadur, Cho, Eui-Sic, Kook, Sung-Ho, Lee, Jeong-Chae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Tissue-Specific Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887089/ https://www.ncbi.nlm.nih.gov/pubmed/36368017 http://dx.doi.org/10.1093/stmcls/sxac080

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