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Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child

Acute pandysautonomia-associated distal esophageal spasm is a rare disease with an unclear etiology. Here, we describe a 12-year-old boy with an acute pandysautonomia-associated distal esophageal spasm who was treated using a peroral endoscopic myotomy (POEM). The patient's clinical features in...

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Autores principales: Zhang, Hanhua, Chi, Biyun, Wang, Fengfan, Shao, Pei, Liu, Huanyu, Fang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887313/
https://www.ncbi.nlm.nih.gov/pubmed/36733769
http://dx.doi.org/10.3389/fped.2022.935915
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author Zhang, Hanhua
Chi, Biyun
Wang, Fengfan
Shao, Pei
Liu, Huanyu
Fang, Ying
author_facet Zhang, Hanhua
Chi, Biyun
Wang, Fengfan
Shao, Pei
Liu, Huanyu
Fang, Ying
author_sort Zhang, Hanhua
collection PubMed
description Acute pandysautonomia-associated distal esophageal spasm is a rare disease with an unclear etiology. Here, we describe a 12-year-old boy with an acute pandysautonomia-associated distal esophageal spasm who was treated using a peroral endoscopic myotomy (POEM). The patient's clinical features included recurrent dysphagia, nausea, vomiting, growth retardation, and signs of autonomic nerve dysfunction (e.g., a decreased production of tears and sweat, and an increased production of saliva). Signs of the distal esophageal spasm were visible in upper gastrointestinal radiography, endoscopy, and high-resolution esophageal manometry. After the POEM, the patient exhibited improvements in nausea and vomiting, and his dysphagia symptoms were relieved by the 6-month follow-up visit. However, the patient's neurological problems persisted. The satisfactory short-term clinical responses in our patient suggest that POEM is feasible, safe, and effective for the treatment of acute pandysautonomia-associated distal esophageal spasms in children.
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spelling pubmed-98873132023-02-01 Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child Zhang, Hanhua Chi, Biyun Wang, Fengfan Shao, Pei Liu, Huanyu Fang, Ying Front Pediatr Pediatrics Acute pandysautonomia-associated distal esophageal spasm is a rare disease with an unclear etiology. Here, we describe a 12-year-old boy with an acute pandysautonomia-associated distal esophageal spasm who was treated using a peroral endoscopic myotomy (POEM). The patient's clinical features included recurrent dysphagia, nausea, vomiting, growth retardation, and signs of autonomic nerve dysfunction (e.g., a decreased production of tears and sweat, and an increased production of saliva). Signs of the distal esophageal spasm were visible in upper gastrointestinal radiography, endoscopy, and high-resolution esophageal manometry. After the POEM, the patient exhibited improvements in nausea and vomiting, and his dysphagia symptoms were relieved by the 6-month follow-up visit. However, the patient's neurological problems persisted. The satisfactory short-term clinical responses in our patient suggest that POEM is feasible, safe, and effective for the treatment of acute pandysautonomia-associated distal esophageal spasms in children. Frontiers Media S.A. 2023-01-17 /pmc/articles/PMC9887313/ /pubmed/36733769 http://dx.doi.org/10.3389/fped.2022.935915 Text en © 2023 Zhang, Chi, Wang, Shao, Liu and Fang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Zhang, Hanhua
Chi, Biyun
Wang, Fengfan
Shao, Pei
Liu, Huanyu
Fang, Ying
Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child
title Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child
title_full Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child
title_fullStr Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child
title_full_unstemmed Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child
title_short Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child
title_sort case report: peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887313/
https://www.ncbi.nlm.nih.gov/pubmed/36733769
http://dx.doi.org/10.3389/fped.2022.935915
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