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sAOP: linking chemical stressors to adverse outcomes pathway networks

MOTIVATION: Adverse outcome pathway (AOP) is a toxicological concept proposed to provide a mechanistic representation of biological perturbation over different layers of biological organization. Although AOPs are by definition chemical-agnostic, many chemical stressors can putatively interfere with...

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Detalles Bibliográficos
Autores principales: Aguayo-Orozco, Alejandro, Audouze, Karine, Siggaard, Troels, Barouki, Robert, Brunak, Søren, Taboureau, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887475/
https://www.ncbi.nlm.nih.gov/pubmed/31329252
http://dx.doi.org/10.1093/bioinformatics/btz570

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