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Numerical Simulation of Surface Plasmon Resonance Optical Fiber Biosensor Enhanced by Using Alloys for Medical Application
Tuberculosis is a very dangerous disease. Therefore, early and quick diagnosis of this disease can increase the chances of overcoming it. Studies show that people with tuberculosis have a lower blood plasma refractive index than healthy people. The performance of the fiber optic sensor based on surf...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887576/ https://www.ncbi.nlm.nih.gov/pubmed/36744008 http://dx.doi.org/10.1007/s11220-022-00409-y |
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author | Esmailidastjerdipour, Parisa Shahshahani, Fateme |
author_facet | Esmailidastjerdipour, Parisa Shahshahani, Fateme |
author_sort | Esmailidastjerdipour, Parisa |
collection | PubMed |
description | Tuberculosis is a very dangerous disease. Therefore, early and quick diagnosis of this disease can increase the chances of overcoming it. Studies show that people with tuberculosis have a lower blood plasma refractive index than healthy people. The performance of the fiber optic sensor based on surface plasmon resonance is investigated for the metal/oxide/graphene structure and for cases where the diameter of the fiber optic core is 300, 600, and 940 µm while blood plasma is considered as the sensing medium. The sensor characteristics such as sensitivity, detection accuracy and figure of merit are simulated for each structure using the theory of matrix method in Wolfram Mathematica software. The simulation results show that the aluminum/lutetium oxide/graphene structure has the highest quality factor when the core diameter of the optical fiber is 940 µm. In continuation of this research, the effects of using alloys with different mixture proportions to improve the quality are investigated. According to results, the structure of aluminum/copper alloy (with a ratio of 30/70)–lutetium oxide graphene is the best choice for improving the quality of the sensor. |
format | Online Article Text |
id | pubmed-9887576 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-98875762023-01-31 Numerical Simulation of Surface Plasmon Resonance Optical Fiber Biosensor Enhanced by Using Alloys for Medical Application Esmailidastjerdipour, Parisa Shahshahani, Fateme Sens Imaging Research Tuberculosis is a very dangerous disease. Therefore, early and quick diagnosis of this disease can increase the chances of overcoming it. Studies show that people with tuberculosis have a lower blood plasma refractive index than healthy people. The performance of the fiber optic sensor based on surface plasmon resonance is investigated for the metal/oxide/graphene structure and for cases where the diameter of the fiber optic core is 300, 600, and 940 µm while blood plasma is considered as the sensing medium. The sensor characteristics such as sensitivity, detection accuracy and figure of merit are simulated for each structure using the theory of matrix method in Wolfram Mathematica software. The simulation results show that the aluminum/lutetium oxide/graphene structure has the highest quality factor when the core diameter of the optical fiber is 940 µm. In continuation of this research, the effects of using alloys with different mixture proportions to improve the quality are investigated. According to results, the structure of aluminum/copper alloy (with a ratio of 30/70)–lutetium oxide graphene is the best choice for improving the quality of the sensor. Springer US 2023-01-31 2023 /pmc/articles/PMC9887576/ /pubmed/36744008 http://dx.doi.org/10.1007/s11220-022-00409-y Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Research Esmailidastjerdipour, Parisa Shahshahani, Fateme Numerical Simulation of Surface Plasmon Resonance Optical Fiber Biosensor Enhanced by Using Alloys for Medical Application |
title | Numerical Simulation of Surface Plasmon Resonance Optical Fiber Biosensor Enhanced by Using Alloys for Medical Application |
title_full | Numerical Simulation of Surface Plasmon Resonance Optical Fiber Biosensor Enhanced by Using Alloys for Medical Application |
title_fullStr | Numerical Simulation of Surface Plasmon Resonance Optical Fiber Biosensor Enhanced by Using Alloys for Medical Application |
title_full_unstemmed | Numerical Simulation of Surface Plasmon Resonance Optical Fiber Biosensor Enhanced by Using Alloys for Medical Application |
title_short | Numerical Simulation of Surface Plasmon Resonance Optical Fiber Biosensor Enhanced by Using Alloys for Medical Application |
title_sort | numerical simulation of surface plasmon resonance optical fiber biosensor enhanced by using alloys for medical application |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887576/ https://www.ncbi.nlm.nih.gov/pubmed/36744008 http://dx.doi.org/10.1007/s11220-022-00409-y |
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