Generation of novel oncolytic vaccinia virus with improved intravenous efficacy through protection against complement-mediated lysis and evasion of neutralization by vaccinia virus-specific antibodies

BACKGROUND: Oncolytic virus immunotherapy has revolutionized cancer immunotherapy by efficiently inducing both oncolysis and systemic immune activation. Locoregional administration has been used for oncolytic virus therapy, but its applications to deep-seated cancers have been limited. Although syst...

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Detalles Bibliográficos
Autores principales: Lee, Namhee, Jeon, Yun-Hui, Yoo, Jiyoon, Shin, Suk-kyung, Lee, Songyi, Park, Mi-Ju, Jung, Byung-Jin, Hong, Yun-Kyoung, Lee, Dong-Sup, Oh, Keunhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887704/
https://www.ncbi.nlm.nih.gov/pubmed/36717184
http://dx.doi.org/10.1136/jitc-2022-006024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887704/
https://www.ncbi.nlm.nih.gov/pubmed/36717184
http://dx.doi.org/10.1136/jitc-2022-006024

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