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PKCβII activation requires nuclear trafficking for phosphorylation and Mdm2-mediated ubiquitination
PKCβII, a conventional PKC family member, plays critical roles in the regulation of a variety of cellular functions. Here, we employed loss-of-function approaches and mutants of PKCβII with altered phosphorylation and protein interaction behaviors to identify the cellular mechanisms underlying the a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Life Science Alliance LLC
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887771/ https://www.ncbi.nlm.nih.gov/pubmed/36717249 http://dx.doi.org/10.26508/lsa.202201748 |