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Jak2/STAT6/c-Myc pathway is vital to the pathogenicity of Philadelphia-positive acute lymphoblastic leukemia caused by P190(BCR-ABL)

BACKGROUND: The Philadelphia chromosome encodes the BCR-ABL fusion protein, which has two primary subtypes, P210 and P190. P210 and P190 cause Philadelphia-positive chronic myeloid leukemia (Ph+ CML) and Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL), respectively. The Ph+ ALL is more...

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Detalles Bibliográficos
Autores principales:	Qin, Run, Wang, Teng, He, Wei, Wei, Wei, Liu, Suotian, Gao, Miao, Huang, Zhenglan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887777/ https://www.ncbi.nlm.nih.gov/pubmed/36721266 http://dx.doi.org/10.1186/s12964-023-01039-x

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