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Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation

BACKGROUND: Sleep loss is a serious global health concern. Consequences include memory deficits and gastrointestinal dysfunction. Our previous research showed that melatonin can effectively improve cognitive impairment and intestinal microbiota disturbances caused by sleep deprivation (SD). The pres...

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Detalles Bibliográficos
Autores principales: Wang, Xintong, Wang, Zixu, Cao, Jing, Dong, Yulan, Chen, Yaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887785/
https://www.ncbi.nlm.nih.gov/pubmed/36721179
http://dx.doi.org/10.1186/s40168-022-01452-3