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Patchouli alcohol attenuates the cognitive deficits in a transgenic mouse model of Alzheimer’s disease via modulating neuropathology and gut microbiota through suppressing C/EBPβ/AEP pathway
BACKGROUND: Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by progressive cognitive dysfunctions and behavioral impairments. Patchouli alcohol (PA), isolated from Pogostemonis Herba, exhibits multiple pharmacological properties, including neuroprotective effects. This...
Autores principales: | Xu, Qing-Qing, Su, Zi-Ren, Yang, Wen, Zhong, Mei, Xian, Yan-Fang, Lin, Zhi-Xiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887791/ https://www.ncbi.nlm.nih.gov/pubmed/36717922 http://dx.doi.org/10.1186/s12974-023-02704-1 |
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