Dynamic single-cell RNA-seq analysis reveals distinct tumor program associated with microenvironmental remodeling and drug sensitivity in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a hematological malignancy characterized by clonal proliferation of malignant plasma cells. Despite extensive research, molecular mechanisms in MM that drive drug sensitivity and clinic outcome remain elusive. RESULTS: Single-cell RNA sequencing was applied to st...

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Detalles Bibliográficos
Autores principales: Chen, Mengping, Wan, Yike, Li, Xin, Xiang, Jing, Chen, Xiaotong, Jiang, Jinxing, Han, Xiaofeng, Zhong, Lu, Xiao, Fei, Liu, Jia, Huang, Honghui, Li, Hua, Liu, Junling, Hou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887807/
https://www.ncbi.nlm.nih.gov/pubmed/36717896
http://dx.doi.org/10.1186/s13578-023-00971-2

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