Cargando…

Forkhead box P3 gene polymorphisms predispose to type 2 diabetes and diabetic nephropathy in the Han Chinese populations: a genetic-association and gender-based evaluation study

BACKGROUND: Functional mutations or polymorphisms affecting forkhead box P3 (FOXP3) can lead to their abnormal FOXP3 gene expression and/or defective Treg cells generation, thus resulting in autoimmune disease and inflammatory disorders. FOXP3 also plays a key role in Type 2 diabetes mellitus (T2DM)...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiaorong, Liu, Zejing, Zhang, Shangdi, Yang, Yinfeng, Wu, Xue, Liu, Xinyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887859/
https://www.ncbi.nlm.nih.gov/pubmed/36717877
http://dx.doi.org/10.1186/s41065-023-00264-1

Ejemplares similares