Variants of a putative baseplate wedge protein extend the host range of Pseudomonas phage K8

BACKGROUND: Narrow host range is a major limitation for phage applications, but phages can evolve expanded host range through adaptations in the receptor-binding proteins. RESULTS: Here, we report that Pseudomonas phage K8 can evolve broader host range and higher killing efficiency at the cost of vi...

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Detalles Bibliográficos
Autores principales: Sun, Li, You, Jiajia, Li, Donghang, Zhang, Zhiqiang, Qin, Xuying, Pang, Wenjing, Li, Peize, Han, Qingzhu, Li, Yueying, Huang, Zhiwei, Zhang, Xixi, Gong, Mengxin, Yang, Hongjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887876/
https://www.ncbi.nlm.nih.gov/pubmed/36721246
http://dx.doi.org/10.1186/s40168-022-01459-w

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