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Benchmarking Bioinformatic Tools for Amplicon-Based Sequencing of Norovirus

In order to survey noroviruses in our environment, it is essential that both wet-lab and computational methods are fit for purpose. Using a simulated sequencing data set, denoising-based (DADA2, Deblur and USEARCH-UNOISE3) and clustering-based pipelines (VSEARCH and FROGS) were compared with respect...

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Detalles Bibliográficos
Autores principales: Fitzpatrick, Amy H., Rupnik, Agnieszka, O’Shea, Helen, Crispie, Fiona, Keaveney, Sinéad, Cotter, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888279/
https://www.ncbi.nlm.nih.gov/pubmed/36541780
http://dx.doi.org/10.1128/aem.01522-22