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Prediction of Busulfan Clearance by Predose Plasma Metabolomic Profiling

Intravenous busulfan doses are often personalized to a target plasma exposure (targeted busulfan) using an individual’s busulfan clearance (BuCL). We evaluated whether BuCL could be predicted by a predose plasma panel of 841 endogenous metabolomic compounds (EMCs). In this prospective cohort of 132...

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Detalles Bibliográficos
Autores principales:	McCune, Jeannine S., Navarro, Sandi L., Baker, K. Scott, Risler, Linda J., Phillips, Brian R., Randolph, Timothy W., Shireman, Laura, Schoch, H. Gary, Deeg, H. Joachim, Zhang, Yuzheng, Men, Alex, Maton, Loes, Huitema, Alwin D. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888309/ https://www.ncbi.nlm.nih.gov/pubmed/36369996 http://dx.doi.org/10.1002/cpt.2794

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