Cargando…
Unlocking life-threatening COVID-19 through two types of inborn errors of type I IFNs
Since 2003, rare inborn errors of human type I IFN immunity have been discovered, each underlying a few severe viral illnesses. Autoantibodies neutralizing type I IFNs due to rare inborn errors of autoimmune regulator (AIRE)–driven T cell tolerance were discovered in 2006, but not initially linked t...
Autores principales: | Casanova, Jean-Laurent, Anderson, Mark S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888384/ https://www.ncbi.nlm.nih.gov/pubmed/36719370 http://dx.doi.org/10.1172/JCI166283 |
Ejemplares similares
-
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
por: Zhang, Qian, et al.
Publicado: (2020) -
Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
por: Zhang, Qian, et al.
Publicado: (2022) -
Inborn errors of TLR3- or MDA5-dependent type I IFN immunity in children with enterovirus rhombencephalitis
por: Chen, Jie, et al.
Publicado: (2021) -
Impaired thymic AIRE expression underlies autoantibodies against type I IFNs in humans with inborn errors of the alternative NF-κB pathway
por: Voyer, Tom Le, et al.
Publicado: (2023) -
Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway
por: Haake, Kathrin, et al.
Publicado: (2020)