Cargando…

Neutrophil CEACAM1 determines susceptibility to NETosis by regulating the S1PR2/S1PR3 axis in liver transplantation

Neutrophils, the largest innate immune cell population in humans, are the primary proinflammatory sentinel in the ischemia-reperfusion injury (IRI) mechanism in orthotopic liver transplantation (OLT). Carcinoembryonic antigen–related cell adhesion molecule 1 (CEACAM1, CC1, or CD66a) is essential in...

Descripción completa

Detalles Bibliográficos
Autores principales: Hirao, Hirofumi, Kojima, Hidenobu, Dery, Kenneth J., Nakamura, Kojiro, Kadono, Kentaro, Zhai, Yuan, Farmer, Douglas G., Kaldas, Fady M., Kupiec-Weglinski, Jerzy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888387/
https://www.ncbi.nlm.nih.gov/pubmed/36719377
http://dx.doi.org/10.1172/JCI162940