Thioredoxin 1 promotes autophagy through transnitrosylation of Atg7 during myocardial ischemia

Modification of cysteine residues by oxidative and nitrosative stress affects structure and function of proteins, thereby contributing to the pathogenesis of cardiovascular disease. Although the major function of thioredoxin 1 (Trx1) is to reduce disulfide bonds, it can also act as either a denitros...

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Detalles Bibliográficos
Autores principales: Nagarajan, Narayani, Oka, Shin-ichi, Nah, Jihoon, Wu, Changgong, Zhai, Peiyong, Mukai, Risa, Xu, Xiaoyong, Kashyap, Sanchita, Huang, Chun-Yang, Sung, Eun-Ah, Mizushima, Wataru, Titus, Allen Sam, Takayama, Koichiro, Mourad, Youssef, Francisco, Jamie, Liu, Tong, Chen, Tong, Li, Hong, Sadoshima, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888389/
https://www.ncbi.nlm.nih.gov/pubmed/36480290
http://dx.doi.org/10.1172/JCI162326

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