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Targeting Kaposi’s sarcoma associated herpesvirus encoded protease (ORF17) by a lysophosphatidic acid molecule for treating KSHV associated diseases

Kaposi’s sarcoma associated herpesvirus (KSHV) is causative agent of Kaposi’s sarcoma, Multicentric Castleman Disease and Pleural effusion lymphoma. KSHV-encoded ORF17 encodes a protease which cleaves -Ala-Ala-, -Ala-Ser- or -Ala-Thr-bonds. The protease plays an important role in assembly and matura...

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Detalles Bibliográficos
Autores principales: Rafeeq, Misbahuddin M, Habib, Alaa Hamed, Nahhas, Alaa F., Binothman, Najat, Aljadani, Majidah, Almulhim, Jawaher, Sain, Ziaullah M, Alam, Mohammad Zubair, Alturki, Norah A, Alam, Qamre, Manish, Manish, Singh, Rajnish Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888664/
https://www.ncbi.nlm.nih.gov/pubmed/36733461
http://dx.doi.org/10.3389/fcell.2023.1060156