Inhibition of mycobacteria proliferation in macrophages by low cisplatin concentration through phosphorylated p53-related apoptosis pathway

BACKGROUND: Drug resistance is a prominent problem in the treatment of tuberculosis, so it is urgent to develop new anti- tuberculosis drugs. Here, we investigated the effects and mechanisms of cisplatin (DDP) on intracellular Mycobacterium smegmatis to tap the therapeutic potential of DDP in mycoba...

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Detalles Bibliográficos
Autores principales: Bao, Jiajia, He, Yonglin, Yang, Chun, Lu, Nan, Li, Anlong, Gao, Sijia, Hosyanto, Felycia Fernanda, Tang, Jialing, Si, Junzhuo, Tang, Xia, Fu, Huichao, Xu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888694/
https://www.ncbi.nlm.nih.gov/pubmed/36719870
http://dx.doi.org/10.1371/journal.pone.0281170

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