A small molecule inhibitor prevents gut bacterial genotoxin production

The human gut bacterial genotoxin colibactin is a possible key driver of colorectal cancer (CRC) development. Understanding colibactin’s biological effects remains difficult owing to the instability of the proposed active species and the complexity of the gut microbiota. Here, we report small molecu...

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Detalles Bibliográficos
Autores principales: Volpe, Matthew R., Velilla, José A., Daniel-Ivad, Martin, Yao, Jenny J., Stornetta, Alessia, Villalta, Peter W., Huang, Hsin-Che, Bachovchin, Daniel A., Balbo, Silvia, Gaudet, Rachelle, Balskus, Emily P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889270/
https://www.ncbi.nlm.nih.gov/pubmed/36253549
http://dx.doi.org/10.1038/s41589-022-01147-8

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