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A paralog of Pcc1 is the fifth core subunit of the KEOPS tRNA-modifying complex in Archaea

In Archaea and Eukaryotes, the synthesis of a universal tRNA modification, N(6)-threonyl-carbamoyl adenosine (t(6)A), is catalyzed by the KEOPS complex composed of Kae1, Bud32, Cgi121, and Pcc1. A fifth subunit, Gon7, is found only in Fungi and Metazoa. Here, we identify and characterize a fifth KEO...

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Detalles Bibliográficos
Autores principales: Daugeron, Marie-Claire, Missoury, Sophia, Da Cunha, Violette, Lazar, Noureddine, Collinet, Bruno, van Tilbeurgh, Herman, Basta, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889334/
https://www.ncbi.nlm.nih.gov/pubmed/36720870
http://dx.doi.org/10.1038/s41467-023-36210-y