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A paralog of Pcc1 is the fifth core subunit of the KEOPS tRNA-modifying complex in Archaea
In Archaea and Eukaryotes, the synthesis of a universal tRNA modification, N(6)-threonyl-carbamoyl adenosine (t(6)A), is catalyzed by the KEOPS complex composed of Kae1, Bud32, Cgi121, and Pcc1. A fifth subunit, Gon7, is found only in Fungi and Metazoa. Here, we identify and characterize a fifth KEO...
Autores principales: | Daugeron, Marie-Claire, Missoury, Sophia, Da Cunha, Violette, Lazar, Noureddine, Collinet, Bruno, van Tilbeurgh, Herman, Basta, Tamara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889334/ https://www.ncbi.nlm.nih.gov/pubmed/36720870 http://dx.doi.org/10.1038/s41467-023-36210-y |
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