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Renal transplant anastomotic time–Every minute counts!

The impact of anastomotic time in renal transplant is under recognized and not well studied. It is one of the few controllable factors that affect the incidence of delayed graft function (DGF). Our study aimed at quantifying the impact of anastomotic time. We performed a retrospective review of 424...

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Autores principales: Mahajan, Nikhil, Heer, Munish K., Trevillian, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889534/
https://www.ncbi.nlm.nih.gov/pubmed/36743673
http://dx.doi.org/10.3389/fmed.2022.1024137
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author Mahajan, Nikhil
Heer, Munish K.
Trevillian, Paul R.
author_facet Mahajan, Nikhil
Heer, Munish K.
Trevillian, Paul R.
author_sort Mahajan, Nikhil
collection PubMed
description The impact of anastomotic time in renal transplant is under recognized and not well studied. It is one of the few controllable factors that affect the incidence of delayed graft function (DGF). Our study aimed at quantifying the impact of anastomotic time. We performed a retrospective review of 424 renal transplants between the years 2006 and 2020. A total of 247 deceased donor renal transplants formed the study cohort. Patients were divided into two groups based on the presence or absence of DGF. Variables with p < 0.3 were analyzed using the binary logistic regression test. The final analysis showed anastomotic time to be significantly associated with DGF with odds ratio of 1.04 per minute corresponding to 4% increase in DGF incidence with every minute increment in anastomotic time. Other variables that had significant impact on DGF were DCD donor (odds ratio – 8.7) and donor terminal creatinine. We concluded that anastomotic time had significant impact on the development of DGF and hence should be minimized.
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spelling pubmed-98895342023-02-02 Renal transplant anastomotic time–Every minute counts! Mahajan, Nikhil Heer, Munish K. Trevillian, Paul R. Front Med (Lausanne) Medicine The impact of anastomotic time in renal transplant is under recognized and not well studied. It is one of the few controllable factors that affect the incidence of delayed graft function (DGF). Our study aimed at quantifying the impact of anastomotic time. We performed a retrospective review of 424 renal transplants between the years 2006 and 2020. A total of 247 deceased donor renal transplants formed the study cohort. Patients were divided into two groups based on the presence or absence of DGF. Variables with p < 0.3 were analyzed using the binary logistic regression test. The final analysis showed anastomotic time to be significantly associated with DGF with odds ratio of 1.04 per minute corresponding to 4% increase in DGF incidence with every minute increment in anastomotic time. Other variables that had significant impact on DGF were DCD donor (odds ratio – 8.7) and donor terminal creatinine. We concluded that anastomotic time had significant impact on the development of DGF and hence should be minimized. Frontiers Media S.A. 2023-01-18 /pmc/articles/PMC9889534/ /pubmed/36743673 http://dx.doi.org/10.3389/fmed.2022.1024137 Text en Copyright © 2023 Mahajan, Heer and Trevillian. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Mahajan, Nikhil
Heer, Munish K.
Trevillian, Paul R.
Renal transplant anastomotic time–Every minute counts!
title Renal transplant anastomotic time–Every minute counts!
title_full Renal transplant anastomotic time–Every minute counts!
title_fullStr Renal transplant anastomotic time–Every minute counts!
title_full_unstemmed Renal transplant anastomotic time–Every minute counts!
title_short Renal transplant anastomotic time–Every minute counts!
title_sort renal transplant anastomotic time–every minute counts!
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889534/
https://www.ncbi.nlm.nih.gov/pubmed/36743673
http://dx.doi.org/10.3389/fmed.2022.1024137
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