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The mechanism of NLRP3 inflammasome activation and its pharmacological inhibitors

NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) is a cytosolic pattern recognition receptor (PRR) that recognizes multiple pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Once activated, NLRP3 initiates the inflammasome assembly together wit...

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Detalles Bibliográficos
Autores principales:	Zhan, Xiaoyan, Li, Qiang, Xu, Guang, Xiao, Xiaohe, Bai, Zhaofang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889537/ https://www.ncbi.nlm.nih.gov/pubmed/36741414 http://dx.doi.org/10.3389/fimmu.2022.1109938

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