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Effects of Sirolimus treatment on patients with β‐Thalassemia: Lymphocyte immunophenotype and biological activity of memory CD4 (+) and CD8 (+) T cells
Inhibitors of the mammalian target of rapamycin (mTOR) have been proposed to improve vaccine responses, especially in the elderly. Accordingly, testing mTOR inhibitors (such as Sirolimus) and other geroprotective drugs might be considered a key strategy to improve overall health resilience of aged p...
Autores principales: | Zurlo, Matteo, Nicoli, Francesco, Proietto, Davide, Dallan, Beatrice, Zuccato, Cristina, Cosenza, Lucia Carmela, Gasparello, Jessica, Papi, Chiara, d'Aversa, Elisabetta, Borgatti, Monica, Scapoli, Chiara, Finotti, Alessia, Gambari, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889681/ https://www.ncbi.nlm.nih.gov/pubmed/36625233 http://dx.doi.org/10.1111/jcmm.17655 |
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