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Effects of Sirolimus treatment on patients with β‐Thalassemia: Lymphocyte immunophenotype and biological activity of memory CD4 (+) and CD8 (+) T cells

Inhibitors of the mammalian target of rapamycin (mTOR) have been proposed to improve vaccine responses, especially in the elderly. Accordingly, testing mTOR inhibitors (such as Sirolimus) and other geroprotective drugs might be considered a key strategy to improve overall health resilience of aged p...

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Detalles Bibliográficos
Autores principales: Zurlo, Matteo, Nicoli, Francesco, Proietto, Davide, Dallan, Beatrice, Zuccato, Cristina, Cosenza, Lucia Carmela, Gasparello, Jessica, Papi, Chiara, d'Aversa, Elisabetta, Borgatti, Monica, Scapoli, Chiara, Finotti, Alessia, Gambari, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889681/
https://www.ncbi.nlm.nih.gov/pubmed/36625233
http://dx.doi.org/10.1111/jcmm.17655

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