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Current understanding of imeglimin action on pancreatic β‐cells: Involvement of mitochondria and endoplasmic reticulum homeostasis
Recent preclinical studies have provided insight on imeglimin's action on pancreatic β‐cells and the mechanisms underlying its clinical benefits. Imeglimin may enhance glucose‐induced insulin secretion (GIIS) and inhibit apoptosis of pancreatic ß‐cells leading to preserved β‐cell mass by mainta...
Autores principales: | Fauzi, Muhammad, Murakami, Takaaki, Yabe, Daisuke, Inagaki, Nobuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889698/ https://www.ncbi.nlm.nih.gov/pubmed/36453164 http://dx.doi.org/10.1111/jdi.13951 |
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