Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of lung cancer

Fibroblasts are poorly characterised cells that variably impact tumour progression. Here, we use single cell RNA-sequencing, multiplexed immunohistochemistry and digital cytometry (CIBERSORTx) to identify and characterise three major fibroblast subpopulations in human non-small cell lung cancer: adv...

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Detalles Bibliográficos
Autores principales: Hanley, Christopher J., Waise, Sara, Ellis, Matthew J., Lopez, Maria A., Pun, Wai Y., Taylor, Julian, Parker, Rachel, Kimbley, Lucy M., Chee, Serena J., Shaw, Emily C., West, Jonathan, Alzetani, Aiman, Woo, Edwin, Ottensmeier, Christian H., Rose-Zerilli, Matthew J. J., Thomas, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889778/
https://www.ncbi.nlm.nih.gov/pubmed/36720863
http://dx.doi.org/10.1038/s41467-023-35832-6

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