Proteogenomics of diffuse gliomas reveal molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms

Diffuse gliomas are devastating brain tumors. Here, we perform a proteogenomic profiling of 213 retrospectively collected glioma tumors. Proteogenomic analysis reveals the downstream biological events leading by EGFR-, IDH1-, TP53-mutations. The comparative analysis illustrates the distinctive featu...

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Detalles Bibliográficos
Autores principales: Wang, Yunzhi, Luo, Rongkui, Zhang, Xuan, Xiang, Hang, Yang, Bing, Feng, Jinwen, Deng, Mengjie, Ran, Peng, Sujie, Akesu, Zhang, Fan, Zhu, Jiajun, Tan, Subei, Xie, Tao, Chen, Pin, Yu, Zixiang, Li, Yan, Jiang, Dongxian, Zhang, Xiaobiao, Zhao, Jian-Yuan, Hou, Yingyong, Ding, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889805/
https://www.ncbi.nlm.nih.gov/pubmed/36720864
http://dx.doi.org/10.1038/s41467-023-36005-1

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