Cargando…

Protective effects of blocking PD-1 pathway on retinal ganglion cells in a mouse model of chronic ocular hypertension

PURPOSE: In this study, we aimed to investigate whether Programmed cell death 1 ligand 1/programmed cell death 1 ligand 2 (PD-L1/PD-L2) double knockout (dKO) has a protective effect on RGCs in a mouse model of chronic ocular hypertension (COHT). METHODS: We used superparamagnetic iron oxide to induc...

Descripción completa

Detalles Bibliográficos
Autores principales: Sheng, Siqi, Ma, Yixian, Zou, Yue, Hu, Fangyuan, Chen, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889850/
https://www.ncbi.nlm.nih.gov/pubmed/36741384
http://dx.doi.org/10.3389/fimmu.2022.1094132