Longitudinal in vivo Ca(2+) imaging reveals dynamic activity changes of diseased retinal ganglion cells at the single-cell level

Retinal ganglion cells (RGCs) are heterogeneous projection neurons that convey distinct visual features from the retina to brain. Here, we present a high-throughput in vivo RGC activity assay in response to light stimulation using noninvasive Ca(2+) imaging of thousands of RGCs simultaneously in liv...

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Detalles Bibliográficos
Autores principales: Li, Liang, Feng, Xue, Fang, Fang, Miller, David A., Zhang, Shaobo, Zhuang, Pei, Huang, Haoliang, Liu, Pingting, Liu, Junting, Sredar, Nripun, Liu, Liang, Sun, Yang, Duan, Xin, Goldberg, Jeffrey L., Zhang, Hao F., Hu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889883/
https://www.ncbi.nlm.nih.gov/pubmed/36409915
http://dx.doi.org/10.1073/pnas.2206829119

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