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Modelling Aotearoa New Zealand's COVID-19 protection framework and the transition away from the elimination strategy

For the first 18 months of the COVID-19 pandemic, New Zealand used an elimination strategy to suppress community transmission of SARS-CoV-2 to zero or very low levels. In late 2021, high vaccine coverage enabled the country to transition away from the elimination strategy to a mitigation strategy. H...

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Autores principales: Vattiato, Giorgia, Lustig, Audrey, Maclaren, Oliver, Binny, Rachelle N., Hendy, Shaun C., Harvey, Emily, O'Neale, Dion, Plank, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890088/
https://www.ncbi.nlm.nih.gov/pubmed/36756071
http://dx.doi.org/10.1098/rsos.220766
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author Vattiato, Giorgia
Lustig, Audrey
Maclaren, Oliver
Binny, Rachelle N.
Hendy, Shaun C.
Harvey, Emily
O'Neale, Dion
Plank, Michael J.
author_facet Vattiato, Giorgia
Lustig, Audrey
Maclaren, Oliver
Binny, Rachelle N.
Hendy, Shaun C.
Harvey, Emily
O'Neale, Dion
Plank, Michael J.
author_sort Vattiato, Giorgia
collection PubMed
description For the first 18 months of the COVID-19 pandemic, New Zealand used an elimination strategy to suppress community transmission of SARS-CoV-2 to zero or very low levels. In late 2021, high vaccine coverage enabled the country to transition away from the elimination strategy to a mitigation strategy. However, given negligible levels of immunity from prior infection, this required careful planning and an effective public health response to avoid uncontrolled outbreaks and unmanageable health impacts. Here, we develop an age-structured model for the Delta variant of SARS-CoV-2 including the effects of vaccination, case isolation, contact tracing, border controls and population-wide control measures. We use this model to investigate how epidemic trajectories may respond to different control strategies, and to explore trade-offs between restrictions in the community and restrictions at the border. We find that a low case tolerance strategy, with a quick change to stricter public health measures in response to increasing cases, reduced the health burden by a factor of three relative to a high tolerance strategy, but almost tripled the time spent in national lockdowns. Increasing the number of border arrivals was found to have a negligible effect on health burden once high vaccination rates were achieved and community transmission was widespread.
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spelling pubmed-98900882023-02-07 Modelling Aotearoa New Zealand's COVID-19 protection framework and the transition away from the elimination strategy Vattiato, Giorgia Lustig, Audrey Maclaren, Oliver Binny, Rachelle N. Hendy, Shaun C. Harvey, Emily O'Neale, Dion Plank, Michael J. R Soc Open Sci Science, Society and Policy For the first 18 months of the COVID-19 pandemic, New Zealand used an elimination strategy to suppress community transmission of SARS-CoV-2 to zero or very low levels. In late 2021, high vaccine coverage enabled the country to transition away from the elimination strategy to a mitigation strategy. However, given negligible levels of immunity from prior infection, this required careful planning and an effective public health response to avoid uncontrolled outbreaks and unmanageable health impacts. Here, we develop an age-structured model for the Delta variant of SARS-CoV-2 including the effects of vaccination, case isolation, contact tracing, border controls and population-wide control measures. We use this model to investigate how epidemic trajectories may respond to different control strategies, and to explore trade-offs between restrictions in the community and restrictions at the border. We find that a low case tolerance strategy, with a quick change to stricter public health measures in response to increasing cases, reduced the health burden by a factor of three relative to a high tolerance strategy, but almost tripled the time spent in national lockdowns. Increasing the number of border arrivals was found to have a negligible effect on health burden once high vaccination rates were achieved and community transmission was widespread. The Royal Society 2023-02-01 /pmc/articles/PMC9890088/ /pubmed/36756071 http://dx.doi.org/10.1098/rsos.220766 Text en © 2023 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited.
spellingShingle Science, Society and Policy
Vattiato, Giorgia
Lustig, Audrey
Maclaren, Oliver
Binny, Rachelle N.
Hendy, Shaun C.
Harvey, Emily
O'Neale, Dion
Plank, Michael J.
Modelling Aotearoa New Zealand's COVID-19 protection framework and the transition away from the elimination strategy
title Modelling Aotearoa New Zealand's COVID-19 protection framework and the transition away from the elimination strategy
title_full Modelling Aotearoa New Zealand's COVID-19 protection framework and the transition away from the elimination strategy
title_fullStr Modelling Aotearoa New Zealand's COVID-19 protection framework and the transition away from the elimination strategy
title_full_unstemmed Modelling Aotearoa New Zealand's COVID-19 protection framework and the transition away from the elimination strategy
title_short Modelling Aotearoa New Zealand's COVID-19 protection framework and the transition away from the elimination strategy
title_sort modelling aotearoa new zealand's covid-19 protection framework and the transition away from the elimination strategy
topic Science, Society and Policy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890088/
https://www.ncbi.nlm.nih.gov/pubmed/36756071
http://dx.doi.org/10.1098/rsos.220766
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