Condensin pinches a short negatively supercoiled DNA loop during each round of ATP usage

Condensin, an SMC (structural maintenance of chromosomes) protein complex, extrudes DNA loops using an ATP‐dependent mechanism that remains to be elucidated. Here, we show how condensin activity alters the topology of the interacting DNA. High condensin concentrations restrain positive DNA supercoil...

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Detalles Bibliográficos
Autores principales: Martínez‐García, Belén, Dyson, Sílvia, Segura, Joana, Ayats, Alba, Cutts, Erin E, Gutierrez‐Escribano, Pilar, Aragón, Luís, Roca, Joaquim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890231/
https://www.ncbi.nlm.nih.gov/pubmed/36533296
http://dx.doi.org/10.15252/embj.2022111913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890231/
https://www.ncbi.nlm.nih.gov/pubmed/36533296
http://dx.doi.org/10.15252/embj.2022111913

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