Cargando…

Theoretical Studies of Leu-Pro-Arg-Asp-Ala Pentapeptide (LPRDA) Binding to Sortase A of Staphylococcus aureus

Sortase A (SrtA) of Staphylococcus aureus is a well-defined molecular target to combat the virulence of these clinically important bacteria. However up to now no efficient drugs or even clinical candidates are known, hence the search for such drugs is still relevant and necessary. SrtA is a complex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shulga, Dmitry A., Kudryavtsev, Konstantin V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890316/ https://www.ncbi.nlm.nih.gov/pubmed/36500275 http://dx.doi.org/10.3390/molecules27238182

Ejemplares similares

Determination of Hexapeptide ALA-ASP-LEU-LYS-PRO-THR by MALDI MS
por: Olejnik, Anna, et al.
Publicado: (2012)

Oligopeptide Sortase Inhibitor Modulates Staphylococcus aureus Cell Adhesion and Biofilm Formation
por: Bozhkova, Svetlana A., et al.
Publicado: (2022)

Effect of the Hydration Shell on the Carbonyl Vibration in the Ala-Leu-Ala-Leu Peptide
por: Hassan, Irtaza, et al.
Publicado: (2021)

Structural Dynamics Behind Clinical Mutants of PncA-Asp12Ala, Pro54Leu, and His57Pro of Mycobacterium tuberculosis Associated With Pyrazinamide Resistance
por: Mehmood, Aamir, et al.
Publicado: (2019)

Substitution of the Lys Linker with the β-Ala Linker Dramatically Decreased the Renal Uptake of (99m)Tc-Labeled Arg-X-Asp-Conjugated and X-Ala-Asp-Conjugated α-Melanocyte Stimulating Hormone Peptides
por: Flook, Adam M., et al.
Publicado: (2014)

Genotype-phenotype correlations of TGFBI p.Leu509Pro, p.Leu509Arg, p.Val613Gly, and the allelic association of p.Met502Val-p.Arg555Gln mutations
por: Niel-Butschi, Florence, et al.
Publicado: (2011)

Baicalin Weakens Staphylococcus aureus Pathogenicity by Targeting Sortase B
por: Wang, Guizhen, et al.
Publicado: (2018)

The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus
por: Chen, Feifei, et al.
Publicado: (2023)

Deterioration after Liver Transplantation and Transthyretin Stabilizer Administration in a Patient with ATTRv Amyloidosis with a Leu58Arg (p.Leu78Arg) TTR Variant
por: Hikishima, Sadao, et al.
Publicado: (2022)

Erianin against Staphylococcus aureus Infection via Inhibiting Sortase A
por: Ouyang, Ping, et al.
Publicado: (2018)

Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A
por: Barthels, Fabian, et al.
Publicado: (2020)

Complete assignment of Ala, Ile, Leu(ProS), Met and Val(ProS) methyl groups of the protruding domain from human norovirus GII.4 Saga
por: Müller-Hermes, Christoph, et al.
Publicado: (2020)

Evaluation of anti-cancer and anti-covid-19 properties of cationic pentapeptide Glu-Gln-Arg-Pro-Arg, from rice bran protein and its d-isomer analogs through molecular docking simulations
por: Gasymov, Oktay K., et al.
Publicado: (2021)

In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A
por: Ham, Hyun Ok, et al.
Publicado: (2016)

Oligopeptide Targeting Sortase A as Potential Anti-infective Therapy for Staphylococcus aureus
por: Wang, Jianfeng, et al.
Publicado: (2018)

Chalcone Attenuates Staphylococcus aureus Virulence by Targeting Sortase A and Alpha-Hemolysin
por: Zhang, Bing, et al.
Publicado: (2017)

Design and Synthesis of Small Molecules as Potent Staphylococcus aureus Sortase A Inhibitors
por: Ha, Min Woo, et al.
Publicado: (2020)

Association of PPARγ2 (Pro12Ala) and Neuropeptide Y (Leu7Pro) Gene Polymorphisms with Obstructive Sleep Apnea in Obese Asian Indians
por: Bhushan, Bharat, et al.
Publicado: (2011)

Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4
por: Lacy, Michael, et al.
Publicado: (2018)

Rice Bran Supplement Containing a Functional Substance, the Novel Peptide Leu-Arg-Ala, Has Anti-Hypertensive Effects: A Double-Blind, Randomized, Placebo-Controlled Study
por: Ogawa, Yutaro, et al.
Publicado: (2019)

(RSS)-[N-Hydroxyethyloxy]-hexafluoroVal–MeLeu–Ala tert-butyl ester
por: Eberle, Marcel K., et al.
Publicado: (2009)

Selection of Promising Novel Fragment Sized S. aureus SrtA Noncovalent Inhibitors Based on QSAR and Docking Modeling Studies
por: Shulga, Dmitry A., et al.
Publicado: (2021)

Quercitrin, an Inhibitor of Sortase A, Interferes with the Adhesion of Staphylococcal aureus
por: Liu, Bingrun, et al.
Publicado: (2015)

Staphylococcus aureus Sortase A-Mediated Incorporation of Peptides: Effect of Peptide Modification on Incorporation
por: Hansenová Maňásková, Silvie, et al.
Publicado: (2016)

Sortase A Mediated Bioconjugation of Common Epitopes Decreases Biofilm Formation in Staphylococcus aureus
por: Kumari, Poonam, et al.
Publicado: (2020)

Natural and Synthetic Sortase A Substrates Are Processed by Staphylococcus aureus via Different Pathways
por: Hansenová Maňásková, Silvie, et al.
Publicado: (2022)

Ameliorative Effects of Peptide Phe-Leu-Ala-Pro on Acute Liver and Kidney Injury Caused by CCl(4) via Attenuation of Oxidative Stress and Inflammation
por: He, Shuqi, et al.
Publicado: (2022)

2-Sulfonylpyrimidines as Privileged Warheads for the Development of S. aureus Sortase A Inhibitors
por: Barthels, Fabian, et al.
Publicado: (2022)

The therapeutic effect of chlorogenic acid against Staphylococcus aureus infection through sortase A inhibition
por: Wang, Lin, et al.
Publicado: (2015)

Novel Inhibitor Discovery of Staphylococcus aureus Sortase B and the Mechanism Confirmation via Molecular Modeling
por: Wang, Guizhen, et al.
Publicado: (2018)

Acacetin Protects Mice from Staphylococcus aureus Bloodstream Infection by Inhibiting the Activity of Sortase A
por: Bi, Chongwei, et al.
Publicado: (2016)

Molecular Mechanism of the Flavonoid Natural Product Dryocrassin ABBA against Staphylococcus aureus Sortase A
por: Zhang, Bing, et al.
Publicado: (2016)

Efficient expression of sortase A from Staphylococcus aureus in Escherichia coli and its enzymatic characterizations
por: Wu, Zhimeng, et al.
Publicado: (2017)

Structure Activity Relationship of the Stem Peptide in Sortase A Mediated Ligation from Staphylococcus aureus
por: Apostolos, Alexis J., et al.
Publicado: (2022)

Structure of N-Terminal Sequence Asp-Ala-Glu-Phe-Arg-His-Asp-Ser of Aβ-Peptide with Phospholipase A(2) from Venom of Andaman Cobra Sub-Species Naja naja sagittifera at 2.0 Å Resolution
por: Mirza, Zeenat, et al.
Publicado: (2014)

Interaction Effects of the Leu162Val PPARα and Pro12Ala PPARγ2 Gene Variants with Renal Function in Metabolic Syndrome Population
por: Mohamed Youssef, Sarraj, et al.
Publicado: (2013)

An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion
Publicado: (1991)

Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors
Publicado: (1988)

Fibronectin receptor of human macrophages recognizes the sequence Arg- Gly-Asp-Ser
Publicado: (1985)

Relevance and application of sortase and sortase-dependent proteins in lactic acid bacteria
por: Call, Emma K., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_hr7qp3rr6b9urcu2o4voqp99c3