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Selectively inhibiting malignant melanoma migration and invasion in an engineered skin model using actin-targeting dinuclear Ru(II)-complexes
Due to the poor prognosis of metastatic cancers, there is a clinical need for agents with anti-metastatic activity. Here we report on the anti-metastatic effect of a previously reported Ru(ii) complex [{(phen)(2)Ru}(2)(tpphz)](4+), 1(4+), that has recently been shown to disrupt actin fiber assembly....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
RSC
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890726/ https://www.ncbi.nlm.nih.gov/pubmed/36755639 http://dx.doi.org/10.1039/d2md00280a |