Pharmacokinetics of a microdosed cocktail of three direct oral anticoagulants in children with congenital heart defects: study protocol for a single-centre clinical trial (DOAC-Child)

INTRODUCTION: Direct oral anticoagulants (DOACs) are direct inhibitors of coagulation factor Xa and are frequently used in adults for different indications such as deep vein thrombosis or non-valvular atrial fibrillation. Paediatric patients might benefit as well from DOACs because the simplicity an...

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Detalles Bibliográficos
Autores principales: Hermann, Simon A, Mikus, Gerd, Chobanyan-Jürgens, Kristine, Gorenflo, Matthias, Ziesenitz, Victoria C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890763/
https://www.ncbi.nlm.nih.gov/pubmed/36720501
http://dx.doi.org/10.1136/bmjpo-2022-001662

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