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Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines
Fused heterocyclic systems containing the pyrimidine ring structure perform a significant role in numerous biological and pharmaceutical processes. Their properties include antibacterial, antifungal, anti-fever, anti-tumor, and antihistamine. As pyridopyrimidines are important in the essential field...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891082/ https://www.ncbi.nlm.nih.gov/pubmed/36756581 http://dx.doi.org/10.1039/d2ra07152e |
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author | Taheri, Maryam Naeimi, Hossein Ghasemi, Amir Hossein |
author_facet | Taheri, Maryam Naeimi, Hossein Ghasemi, Amir Hossein |
author_sort | Taheri, Maryam |
collection | PubMed |
description | Fused heterocyclic systems containing the pyrimidine ring structure perform a significant role in numerous biological and pharmaceutical processes. Their properties include antibacterial, antifungal, anti-fever, anti-tumor, and antihistamine. As pyridopyrimidines are important in the essential fields of pharmaceutical chemistry, efficient methods for preparing these heterocycles are presented. In this study, a method for producing improved hollow carbon sphere nanostructures with cobalt and nickel (Co-Ni@HCSs) is presented. The nanocatalyst was prepared and identified by applying Fourier-transform infrared spectroscopy (FT-IR), X-ray powder diffraction (XRD), field-emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDS), Brunauer–Emmett–Teller (BET), and elemental mapping techniques. The Co-Ni@HCSs nanocatalyst was proved to be highly efficient in synthesizing pyranopyrimidine derivatives. The sizeable active site, economic catalyst loading, easy workup, reusability, green reaction conditions, and excellent yields of all derivatives are some of the significant features of this process. Also, applying response surface methodology (RSM) and the Box–Behnken design (BBD) techniques allowed us to determine the influential factors of the laboratory variables and identify the optimum conditions for superior catalytic activity. Finally, synthesized organic compounds were identified by utilizing melting point, FT-IR, and hydrogen-1 nuclear magnetic resonance ((1)H NMR) analyses. |
format | Online Article Text |
id | pubmed-9891082 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-98910822023-02-07 Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines Taheri, Maryam Naeimi, Hossein Ghasemi, Amir Hossein RSC Adv Chemistry Fused heterocyclic systems containing the pyrimidine ring structure perform a significant role in numerous biological and pharmaceutical processes. Their properties include antibacterial, antifungal, anti-fever, anti-tumor, and antihistamine. As pyridopyrimidines are important in the essential fields of pharmaceutical chemistry, efficient methods for preparing these heterocycles are presented. In this study, a method for producing improved hollow carbon sphere nanostructures with cobalt and nickel (Co-Ni@HCSs) is presented. The nanocatalyst was prepared and identified by applying Fourier-transform infrared spectroscopy (FT-IR), X-ray powder diffraction (XRD), field-emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDS), Brunauer–Emmett–Teller (BET), and elemental mapping techniques. The Co-Ni@HCSs nanocatalyst was proved to be highly efficient in synthesizing pyranopyrimidine derivatives. The sizeable active site, economic catalyst loading, easy workup, reusability, green reaction conditions, and excellent yields of all derivatives are some of the significant features of this process. Also, applying response surface methodology (RSM) and the Box–Behnken design (BBD) techniques allowed us to determine the influential factors of the laboratory variables and identify the optimum conditions for superior catalytic activity. Finally, synthesized organic compounds were identified by utilizing melting point, FT-IR, and hydrogen-1 nuclear magnetic resonance ((1)H NMR) analyses. The Royal Society of Chemistry 2023-01-25 /pmc/articles/PMC9891082/ /pubmed/36756581 http://dx.doi.org/10.1039/d2ra07152e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Taheri, Maryam Naeimi, Hossein Ghasemi, Amir Hossein Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines |
title | Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines |
title_full | Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines |
title_fullStr | Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines |
title_full_unstemmed | Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines |
title_short | Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines |
title_sort | preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891082/ https://www.ncbi.nlm.nih.gov/pubmed/36756581 http://dx.doi.org/10.1039/d2ra07152e |
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