Systematic comparison of HIV-1 Envelope-specific IgG responses induced by different vaccination regimens: Can we steer IgG recognition towards regions of viral vulnerability?

Immunogens and vaccination regimens can influence patterns of immune-epitope recognition, steering them towards or away from epitopes of potential viral vulnerability. HIV-1 envelope (Env)-specific antibodies targeting variable region 2 (V2) or 3 (V3) correlated with protection during the RV144 tria...

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Detalles Bibliográficos
Autores principales: Horvath, Augusta, Rogers, Lisa, Pollakis, Georgios, Baranov, Olga, Pieroth, Nora, Joseph, Sarah, Chachage, Mkunde, Heitzer, Asli, Maganga, Lucas, Msafiri, Frank, Joachim, Agricola, Viegas, Edna, Eller, Leigh-Anne, Kibuuka, Hannah, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayapan, Sorachai, Dhitavat, Jittima, Premsri, Nakorn, Fidler, Sarah, Shattock, Robin J., Robb, Merlin Lee, Weber, Jonathan, McCormack, Sheena, Munseri, Patricia Jane, Lyamuya, Eligius, Nilsson, Charlotta, Kroidl, Arne, Hoelscher, Michael, Wagner, Ralf, Geldmacher, Christof, Held, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891136/
https://www.ncbi.nlm.nih.gov/pubmed/36741409
http://dx.doi.org/10.3389/fimmu.2022.1075606

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