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mRNA ageing shapes the Cap2 methylome in mammalian mRNA

The mRNA cap structure is a major site of dynamic mRNA methylation. mRNA caps exist in either the Cap1 or Cap2 form, depending on the presence of 2′-O-methylation on the first transcribed nucleotide or both the first and second transcribed nucleotides, respectively(1,2). However, the identity of Cap...

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Detalles Bibliográficos
Autores principales: Despic, Vladimir, Jaffrey, Samie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891201/
https://www.ncbi.nlm.nih.gov/pubmed/36725932
http://dx.doi.org/10.1038/s41586-022-05668-z

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