Fusobacterium nucleatum induces MDSCs enrichment via activation the NLRP3 inflammosome in ESCC cells, leading to cisplatin resistance

BACKGROUND: To analyse the regulatory effect of Fusobacterium nucleatum (Fn) on NOD-like receptor protein 3 (NLRP3) and myeloid-derived suppressor cells (MDSCs) in oesophageal squamous cell carcinoma (ESCC) as well as its effect on cisplatin (CDDP) therapy and to explore its clinical significance. M...

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Detalles Bibliográficos
Autores principales: Liang, Mengxia, Liu, Yiwen, Zhang, Zheyuan, Yang, Haijun, Dai, Ningtao, Zhang, Ning, Sun, Wei, Guo, Yibo, Kong, Jinyu, Wang, Xiaopeng, Wang, Min, Zhou, Fuyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891225/
https://www.ncbi.nlm.nih.gov/pubmed/35435776
http://dx.doi.org/10.1080/07853890.2022.2061045

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