Unilateral Linear Lichen Planus Pigmentosus Responding to Isotretinoin: A Case Report

Lichen planus pigmentosus (LPP) is a rare variant of lichen planus. Due to the scarce number of patients diagnosed with LPP, there are no treatment guidelines. Multiple topical and oral agents are utilized in LPP with varying degrees of response. Isotretinoin has only been investigated in a case rep...

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Autores principales: Alghamdi, Fadi, Alghamdi, Yara, Aleissa, Abdulellah I, AlQurashi, Wasan, Alharbi, Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891236/
https://www.ncbi.nlm.nih.gov/pubmed/36741605
http://dx.doi.org/10.7759/cureus.33255
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author Alghamdi, Fadi
Alghamdi, Yara
Aleissa, Abdulellah I
AlQurashi, Wasan
Alharbi, Abdullah
author_facet Alghamdi, Fadi
Alghamdi, Yara
Aleissa, Abdulellah I
AlQurashi, Wasan
Alharbi, Abdullah
author_sort Alghamdi, Fadi
collection PubMed
description Lichen planus pigmentosus (LPP) is a rare variant of lichen planus. Due to the scarce number of patients diagnosed with LPP, there are no treatment guidelines. Multiple topical and oral agents are utilized in LPP with varying degrees of response. Isotretinoin has only been investigated in a case report and a single prospective pilot study for managing LPP. Herein, we report the efficacy, safety, and moderate improvement of LPP patients on isotretinoin 20 mg (0.25 mg/kg), topical adapalene gel, 4% hydroquinone cream, and topical sunscreen.
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spelling pubmed-98912362023-02-02 Unilateral Linear Lichen Planus Pigmentosus Responding to Isotretinoin: A Case Report Alghamdi, Fadi Alghamdi, Yara Aleissa, Abdulellah I AlQurashi, Wasan Alharbi, Abdullah Cureus Dermatology Lichen planus pigmentosus (LPP) is a rare variant of lichen planus. Due to the scarce number of patients diagnosed with LPP, there are no treatment guidelines. Multiple topical and oral agents are utilized in LPP with varying degrees of response. Isotretinoin has only been investigated in a case report and a single prospective pilot study for managing LPP. Herein, we report the efficacy, safety, and moderate improvement of LPP patients on isotretinoin 20 mg (0.25 mg/kg), topical adapalene gel, 4% hydroquinone cream, and topical sunscreen. Cureus 2023-01-02 /pmc/articles/PMC9891236/ /pubmed/36741605 http://dx.doi.org/10.7759/cureus.33255 Text en Copyright © 2023, Alghamdi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Alghamdi, Fadi
Alghamdi, Yara
Aleissa, Abdulellah I
AlQurashi, Wasan
Alharbi, Abdullah
Unilateral Linear Lichen Planus Pigmentosus Responding to Isotretinoin: A Case Report
title Unilateral Linear Lichen Planus Pigmentosus Responding to Isotretinoin: A Case Report
title_full Unilateral Linear Lichen Planus Pigmentosus Responding to Isotretinoin: A Case Report
title_fullStr Unilateral Linear Lichen Planus Pigmentosus Responding to Isotretinoin: A Case Report
title_full_unstemmed Unilateral Linear Lichen Planus Pigmentosus Responding to Isotretinoin: A Case Report
title_short Unilateral Linear Lichen Planus Pigmentosus Responding to Isotretinoin: A Case Report
title_sort unilateral linear lichen planus pigmentosus responding to isotretinoin: a case report
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891236/
https://www.ncbi.nlm.nih.gov/pubmed/36741605
http://dx.doi.org/10.7759/cureus.33255
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AT alqurashiwasan unilaterallinearlichenplanuspigmentosusrespondingtoisotretinoinacasereport
AT alharbiabdullah unilaterallinearlichenplanuspigmentosusrespondingtoisotretinoinacasereport

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