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GWAS quality score for evaluating associated regions in GWAS analyses

MOTIVATION: The number of significantly associated regions reported in genome-wide association studies (GWAS) for polygenic traits typically increases with sample size. A traditional tool for quality control and identification of significant regions has been a visual inspection of how significant an...

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Detalles Bibliográficos
Autores principales: Awasthi, Swapnil, Chen, Chia-Yen, Lam, Max, Huang, Hailiang, Ripke, Stephan, Altar, C Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891241/
https://www.ncbi.nlm.nih.gov/pubmed/36651666
http://dx.doi.org/10.1093/bioinformatics/btad004

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