Inhibition of Bruton’s Tyrosine Kinase Activity Attenuates Hemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats

The aim of this study was to investigate (a) the potential of the Bruton's tyrosine kinase (BTK) inhibitors acalabrutinib and fenebrutinib to reduce multiple organ dysfunction syndrome (MODS) in acute (short-term and long-term follow-up) hemorrhagic shock (HS) rat models and (b) whether treatme...

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Detalles Bibliográficos
Autores principales: Patel, Nikita M., Oliveira, Filipe R. M. B., Ramos, Hanna Pillmann, Aimaretti, Eleonora, Alves, Gustavo Ferreira, Coldewey, Sina M., Collino, Massimo, Sordi, Regina, Thiemermann, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891276/
https://www.ncbi.nlm.nih.gov/pubmed/35129479
http://dx.doi.org/10.1097/SLA.0000000000005357

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