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Limitations of radiosensitization by direct telomerase inhibition to treat high-risk medulloblastoma
Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Previous studies have elucidated the genomic landscape of MB leading to the recognition of four core molecular subgroups (WNT, SHH, group 3 and group 4) with distinct clinical outcomes. Group 3 has the worst prognosis of all MB...
Autores principales: | Sengupta, Satarupa, Senthil Kumar, Shiva, Bondra, Kathryn, Sobo, Matthew, Mo, Xiaokui, Drissi, Rachid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891285/ https://www.ncbi.nlm.nih.gov/pubmed/36741010 http://dx.doi.org/10.3389/fonc.2023.1104670 |
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