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Limitations of radiosensitization by direct telomerase inhibition to treat high-risk medulloblastoma

Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Previous studies have elucidated the genomic landscape of MB leading to the recognition of four core molecular subgroups (WNT, SHH, group 3 and group 4) with distinct clinical outcomes. Group 3 has the worst prognosis of all MB...

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Detalles Bibliográficos
Autores principales: Sengupta, Satarupa, Senthil Kumar, Shiva, Bondra, Kathryn, Sobo, Matthew, Mo, Xiaokui, Drissi, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891285/
https://www.ncbi.nlm.nih.gov/pubmed/36741010
http://dx.doi.org/10.3389/fonc.2023.1104670

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