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Pediatric Thyroidectomy: Experience From a Portuguese Hospital

Background and objective Pediatric thyroid disease requiring surgery is rare. Thyroid nodules are a frequent indication for surgery and are mostly benign. However, up to 25% of cases can be malignant. In this study, we aimed to describe our center’s experience with regard to pediatric thyroid surger...

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Autores principales: Vieira, Paula Manuel, Barbosa Sequeira, Joana, Santos Monteiro, Sílvia, De Carvalho Vaz, Ana, da Silva Cardoso, Juliana, Ribeiro, Luís, Mendes, Catarina, Freitas, Joana, Ribeiro de Castro, João, Borges, Teresa, Oliveira, Maria João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891316/
https://www.ncbi.nlm.nih.gov/pubmed/36741645
http://dx.doi.org/10.7759/cureus.33259
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author Vieira, Paula Manuel
Barbosa Sequeira, Joana
Santos Monteiro, Sílvia
De Carvalho Vaz, Ana
da Silva Cardoso, Juliana
Ribeiro, Luís
Mendes, Catarina
Freitas, Joana
Ribeiro de Castro, João
Borges, Teresa
Oliveira, Maria João
author_facet Vieira, Paula Manuel
Barbosa Sequeira, Joana
Santos Monteiro, Sílvia
De Carvalho Vaz, Ana
da Silva Cardoso, Juliana
Ribeiro, Luís
Mendes, Catarina
Freitas, Joana
Ribeiro de Castro, João
Borges, Teresa
Oliveira, Maria João
author_sort Vieira, Paula Manuel
collection PubMed
description Background and objective Pediatric thyroid disease requiring surgery is rare. Thyroid nodules are a frequent indication for surgery and are mostly benign. However, up to 25% of cases can be malignant. In this study, we aimed to describe our center’s experience with regard to pediatric thyroid surgery. Methods This was a retrospective transverse study involving pediatric patients who underwent thyroid surgery at a tertiary hospital between January 2010 and December 2021. Results A total of 14 patients underwent 15 surgeries. The main reason for referral to pediatric endocrinology was thyroid nodules (n=10). Thirteen fine needle aspirations (FNAs) were performed, with follicular tumor (n=6) being the most common finding. The median age of patients at surgery was 15.9 years [interquartile range (IQR): 14.0-16.8]. The most common surgical indications were the presence of a follicular tumor on FNA (n=5) and thyroid nodule size causing symptoms (n=5). There was one case of prophylactic thyroidectomy due to the identification of a multiple endocrine neoplasia type 2A (MEN2A) mutation. The most frequently described histopathology results were follicular adenoma (n=6) and colloid nodular goiter (n=6). Three postoperative complications were observed in three different patients: bilateral lesion of the recurrent laryngeal nerve, cervical hematoma, and transient hypoparathyroidism with hypocalcemia. Conclusion In our study, the most frequent surgical indication was a follicular tumor. A good correlation was found between FNA cytology and final histopathology results, which is in accordance with previous studies. This reinforces the importance of FNA in diagnosis and surgical planning. The rate of complications in our study is comparable to that in larger single-center series in the literature.
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spelling pubmed-98913162023-02-02 Pediatric Thyroidectomy: Experience From a Portuguese Hospital Vieira, Paula Manuel Barbosa Sequeira, Joana Santos Monteiro, Sílvia De Carvalho Vaz, Ana da Silva Cardoso, Juliana Ribeiro, Luís Mendes, Catarina Freitas, Joana Ribeiro de Castro, João Borges, Teresa Oliveira, Maria João Cureus Endocrinology/Diabetes/Metabolism Background and objective Pediatric thyroid disease requiring surgery is rare. Thyroid nodules are a frequent indication for surgery and are mostly benign. However, up to 25% of cases can be malignant. In this study, we aimed to describe our center’s experience with regard to pediatric thyroid surgery. Methods This was a retrospective transverse study involving pediatric patients who underwent thyroid surgery at a tertiary hospital between January 2010 and December 2021. Results A total of 14 patients underwent 15 surgeries. The main reason for referral to pediatric endocrinology was thyroid nodules (n=10). Thirteen fine needle aspirations (FNAs) were performed, with follicular tumor (n=6) being the most common finding. The median age of patients at surgery was 15.9 years [interquartile range (IQR): 14.0-16.8]. The most common surgical indications were the presence of a follicular tumor on FNA (n=5) and thyroid nodule size causing symptoms (n=5). There was one case of prophylactic thyroidectomy due to the identification of a multiple endocrine neoplasia type 2A (MEN2A) mutation. The most frequently described histopathology results were follicular adenoma (n=6) and colloid nodular goiter (n=6). Three postoperative complications were observed in three different patients: bilateral lesion of the recurrent laryngeal nerve, cervical hematoma, and transient hypoparathyroidism with hypocalcemia. Conclusion In our study, the most frequent surgical indication was a follicular tumor. A good correlation was found between FNA cytology and final histopathology results, which is in accordance with previous studies. This reinforces the importance of FNA in diagnosis and surgical planning. The rate of complications in our study is comparable to that in larger single-center series in the literature. Cureus 2023-01-02 /pmc/articles/PMC9891316/ /pubmed/36741645 http://dx.doi.org/10.7759/cureus.33259 Text en Copyright © 2023, Vieira et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Vieira, Paula Manuel
Barbosa Sequeira, Joana
Santos Monteiro, Sílvia
De Carvalho Vaz, Ana
da Silva Cardoso, Juliana
Ribeiro, Luís
Mendes, Catarina
Freitas, Joana
Ribeiro de Castro, João
Borges, Teresa
Oliveira, Maria João
Pediatric Thyroidectomy: Experience From a Portuguese Hospital
title Pediatric Thyroidectomy: Experience From a Portuguese Hospital
title_full Pediatric Thyroidectomy: Experience From a Portuguese Hospital
title_fullStr Pediatric Thyroidectomy: Experience From a Portuguese Hospital
title_full_unstemmed Pediatric Thyroidectomy: Experience From a Portuguese Hospital
title_short Pediatric Thyroidectomy: Experience From a Portuguese Hospital
title_sort pediatric thyroidectomy: experience from a portuguese hospital
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891316/
https://www.ncbi.nlm.nih.gov/pubmed/36741645
http://dx.doi.org/10.7759/cureus.33259
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