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Identification and functional characterization of imbalanced osteoarthritis-associated fibronectin splice variants

OBJECTIVE: To identify FN1 transcripts associated with OA pathophysiology and investigate the downstream effects of modulating FN1 expression and relative transcript ratio. METHODS: FN1 transcriptomic data was obtained from our previously assessed RNA-seq dataset of lesioned and preserved OA cartila...

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Detalles Bibliográficos
Autores principales:	van Hoolwerff, Marcella, Tuerlings, Margo, Wijnen, Imke J L, Suchiman, H Eka D, Cats, Davy, Mei, Hailiang, Nelissen, Rob G H H, van der Linden–van der Zwaag, Henrike M J, Ramos, Yolande F M, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891405/ https://www.ncbi.nlm.nih.gov/pubmed/35532170 http://dx.doi.org/10.1093/rheumatology/keac272

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