Cargando…

Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica

OBJECTIVES: PMR causes pain, stiffness and disability in older adults. Measuring the impact of the condition from the patient’s perspective is vital to high-quality research and patient-centred care, yet there are no validated patient-reported outcome measures (PROMs) for PMR. We set out to develop...

Descripción completa

Detalles Bibliográficos
Autores principales: Twohig, Helen, Mitchell, Caroline, Mallen, Christian D, Muller, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891434/
https://www.ncbi.nlm.nih.gov/pubmed/35639659
http://dx.doi.org/10.1093/rheumatology/keac317
_version_ 1784881135258435584
author Twohig, Helen
Mitchell, Caroline
Mallen, Christian D
Muller, Sara
author_facet Twohig, Helen
Mitchell, Caroline
Mallen, Christian D
Muller, Sara
author_sort Twohig, Helen
collection PubMed
description OBJECTIVES: PMR causes pain, stiffness and disability in older adults. Measuring the impact of the condition from the patient’s perspective is vital to high-quality research and patient-centred care, yet there are no validated patient-reported outcome measures (PROMs) for PMR. We set out to develop and psychometrically evaluate a PMR-specific PROM. METHODS: Two cross-sectional postal surveys of people with a confirmed diagnosis of PMR were used to provide data for field testing and psychometric evaluation. A total of 256 participants completed the draft PROM. Distribution of item responses was examined, and exploratory factor analysis and Rasch analysis were used to inform item reduction, formation of dimension structure and scoring system development. Some 179 participants completed the PROM at two time points, along with comparator questionnaires and anchor questions. Test–retest reliability, construct validity and responsiveness were evaluated. RESULTS: Results from the field-testing study led to the formation of the PMR-Impact Scale (PMR-IS), comprising four domains (symptoms, function, psychological and emotional well-being, and steroid side effects). Construct validity and test–retest reliability met accepted quality criteria for each domain. There was insufficient evidence from this study to determine its ability to detect flares/deterioration, but the PMR-IS was responsive to improvements in the condition. CONCLUSION: The PMR-IS offers researchers a new way to assess patient-reported outcomes in clinical studies of PMR. It has been developed robustly, with patient input at every stage. It has good construct validity and test–retest reliability. Further work is needed to fully establish its responsiveness and interpretability parameters, and to assess its real-world clinical utility.
format Online
Article
Text
id pubmed-9891434
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-98914342023-02-02 Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica Twohig, Helen Mitchell, Caroline Mallen, Christian D Muller, Sara Rheumatology (Oxford) Clinical Science OBJECTIVES: PMR causes pain, stiffness and disability in older adults. Measuring the impact of the condition from the patient’s perspective is vital to high-quality research and patient-centred care, yet there are no validated patient-reported outcome measures (PROMs) for PMR. We set out to develop and psychometrically evaluate a PMR-specific PROM. METHODS: Two cross-sectional postal surveys of people with a confirmed diagnosis of PMR were used to provide data for field testing and psychometric evaluation. A total of 256 participants completed the draft PROM. Distribution of item responses was examined, and exploratory factor analysis and Rasch analysis were used to inform item reduction, formation of dimension structure and scoring system development. Some 179 participants completed the PROM at two time points, along with comparator questionnaires and anchor questions. Test–retest reliability, construct validity and responsiveness were evaluated. RESULTS: Results from the field-testing study led to the formation of the PMR-Impact Scale (PMR-IS), comprising four domains (symptoms, function, psychological and emotional well-being, and steroid side effects). Construct validity and test–retest reliability met accepted quality criteria for each domain. There was insufficient evidence from this study to determine its ability to detect flares/deterioration, but the PMR-IS was responsive to improvements in the condition. CONCLUSION: The PMR-IS offers researchers a new way to assess patient-reported outcomes in clinical studies of PMR. It has been developed robustly, with patient input at every stage. It has good construct validity and test–retest reliability. Further work is needed to fully establish its responsiveness and interpretability parameters, and to assess its real-world clinical utility. Oxford University Press 2022-05-26 /pmc/articles/PMC9891434/ /pubmed/35639659 http://dx.doi.org/10.1093/rheumatology/keac317 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the British Society for Rheumatology. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Science
Twohig, Helen
Mitchell, Caroline
Mallen, Christian D
Muller, Sara
Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica
title Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica
title_full Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica
title_fullStr Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica
title_full_unstemmed Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica
title_short Development and psychometric evaluation of the PMR-Impact Scale: a new patient reported outcome measure for polymyalgia rheumatica
title_sort development and psychometric evaluation of the pmr-impact scale: a new patient reported outcome measure for polymyalgia rheumatica
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891434/
https://www.ncbi.nlm.nih.gov/pubmed/35639659
http://dx.doi.org/10.1093/rheumatology/keac317
work_keys_str_mv AT twohighelen developmentandpsychometricevaluationofthepmrimpactscaleanewpatientreportedoutcomemeasureforpolymyalgiarheumatica
AT mitchellcaroline developmentandpsychometricevaluationofthepmrimpactscaleanewpatientreportedoutcomemeasureforpolymyalgiarheumatica
AT mallenchristiand developmentandpsychometricevaluationofthepmrimpactscaleanewpatientreportedoutcomemeasureforpolymyalgiarheumatica
AT mullersara developmentandpsychometricevaluationofthepmrimpactscaleanewpatientreportedoutcomemeasureforpolymyalgiarheumatica