Cargando…

Effects of genetic polymorphisms on methotrexate levels and toxicity in Chinese patients with acute lymphoblastic leukemia

Methotrexate (MTX) has an antitumor effect when used for the treatment of acute lymphoblastic leukemia (ALL). This study aims at evaluating the associations between 14 polymorphisms of six genes involved in MTX metabolism with serum MTX concentration and toxicity accompanying high-dose MTX. Polymorp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hao, Qishan, Song, Yang, Fang, Qiuyun, Lin, Yani, Chen, Long, Wang, Xiaodan, Zhang, Ping, Wang, Zhe, Gong, Xiaoyuan, Liu, Kaiqi, Li, Qinghua, Tian, Zheng, Wang, Min, Wang, Jianxiang, Mi, Yingchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891445/ https://www.ncbi.nlm.nih.gov/pubmed/36742186 http://dx.doi.org/10.1097/BS9.0000000000000142

Ejemplares similares

The clinical characteristics and prognosis in adult Ph negative acute lymphoblastic leukemia with TP53 aberrations
por: Fang, Qiuyun, et al.
Publicado: (2022)

Gene Deletions and Prognostic Values in B-Linage Acute Lymphoblastic Leukemia
por: Fang, Qiuyun, et al.
Publicado: (2021)

Spectrum of somatic mutations detected by targeted next-generation sequencing and their prognostic significance in adult patients with acute lymphoblastic leukemia
por: Feng, Juan, et al.
Publicado: (2017)

The impact of venetoclax based regimens in the preemptive of measurable residual disease in acute myeloid leukemia
por: Fang, Qiuyun, et al.
Publicado: (2022)

Prognostic significance of copy number variation in B-cell acute lymphoblastic leukemia
por: Song, Yang, et al.
Publicado: (2022)

Association between high-dose methotrexate-induced toxicity and polymorphisms within methotrexate pathway genes in acute lymphoblastic leukemia
por: Xu, Meng, et al.
Publicado: (2022)

Polymorphisms in methotrexate transporters and their relationship to plasma methotrexate levels, toxicity of high-dose methotrexate, and outcome of pediatric acute lymphoblastic leukemia
por: Liu, Shu-Guang, et al.
Publicado: (2017)

Chimeric antigen receptor-modified T-cell therapy for bone marrow and skin relapse Philadelphia chromosome-like acute lymphoblastic leukemia: A case report
por: Yang, Mianzeng, et al.
Publicado: (2020)

Association of microRNA Polymorphisms with Toxicities Induced by Methotrexate in Children with Acute Lymphoblastic Leukemia
por: Karpa, Vasiliki, et al.
Publicado: (2023)

Comparison of multi-omics results between patients with acute myeloid leukemia with long-term survival and healthy controls
por: Song, Yang, et al.
Publicado: (2022)

Efficacy of combination of venetoclax with azacitidine or chemotherapy in refractory/relapse acute leukemias of ambiguous lineage, not otherwise specified
por: Liu, Kaiqi, et al.
Publicado: (2021)

Mature plasmacytoid dendritic cells associated with acute myeloid leukemia show similar genetic mutations and expression profiles to leukemia cells
por: Gong, Xiaoyuan, et al.
Publicado: (2022)

Impact of microRNA polymorphisms on high-dose methotrexate-related hematological toxicities in pediatric acute lymphoblastic leukemia
por: Zhan, Min, et al.
Publicado: (2023)

The influence of MTHFR genetic polymorphisms on methotrexate therapy in pediatric acute lymphoblastic leukemia
por: Shen, Yaqing, et al.
Publicado: (2021)

Polymorphisms within methotrexate pathway genes: Relationship between plasma methotrexate levels, toxicity experienced and outcome in pediatric acute lymphoblastic leukemia
por: Esmaili, Mohammad Ali, et al.
Publicado: (2020)

High-Dose Cytarabine in Acute Myeloid Leukemia Treatment: A Systematic Review and Meta-Analysis
por: Li, Wei, et al.
Publicado: (2014)

Association of ABCC2 −24C>T Polymorphism with High-Dose Methotrexate Plasma Concentrations and Toxicities in Childhood Acute Lymphoblastic Leukemia
por: Liu, Yan, et al.
Publicado: (2014)

Treatment of STAT5b-RARA positive acute promyelocytic leukemia by Venetoclax combining with homoharringtonine, cytarabine: A case report and literature review
por: Zhang, Guangji, et al.
Publicado: (2022)

MTHFR polymorphisms in childhood acute lymphoblastic leukemia: influence on methotrexate therapy
por: Umerez, Maitane, et al.
Publicado: (2017)

Efficacy and safety of CD19 CAR T constructed with a new anti-CD19 chimeric antigen receptor in relapsed or refractory acute lymphoblastic leukemia
por: Gu, Runxia, et al.
Publicado: (2020)

Population Pharmacokinetics of High-Dose Methotrexate in Chinese Pediatric Patients With Acute Lymphoblastic Leukemia
por: Gao, Xuan, et al.
Publicado: (2021)

Distinct genetic alteration profiles of acute myeloid leukemia between Caucasian and Eastern Asian population
por: Wei, Hui, et al.
Publicado: (2018)

Influence of Folate-Related Gene Polymorphisms on High-Dose Methotrexate-Related Toxicity and Prognosis in Turkish Children with Acute Lymphoblastic Leukemia
por: Yazıcıoğlu, Burcu, et al.
Publicado: (2017)

Diagnostic challenge in mixed phenotype acute leukemia with T/megakaryocyte or T/myeloid lineages accompanied by t(3;3)
por: Jia, Yannan, et al.
Publicado: (2022)

Candidemia in Patients with Acute Leukemia: Analysis of 7 Years’ Experience at a Single Center in China
por: Gong, Xiaoyuan, et al.
Publicado: (2020)

An analysis of 97 previously diagnosed de novo adult acute erythroid leukemia patients following the 2016 revision to World Health Organization classification
por: Qiu, Shaowei, et al.
Publicado: (2017)

Identifying risk factors for high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia
por: Li, Xiao, et al.
Publicado: (2019)

Correction: Association of ABCC2 -24C>T Polymorphism with High-Dose Methotrexate Plasma Concentrations and Toxicities in Childhood Acute Lymphoblastic Leukemia
Publicado: (2014)

ITPA Polymorphisms and the Incidence of Toxicities in Children with Acute Lymphoblastic Leukemia
por: Svasdisant, Patpetra, et al.
Publicado: (2023)

Benefit of intermediate-dose cytarabine-containing induction in molecular subgroups of acute myeloid leukemia
por: Wei, Hui, et al.
Publicado: (2020)

The number of CD34+CD38+CD117+HLA-DR+CD13+CD33+ cells indicates post-chemotherapy hematopoietic recovery in patients with acute myeloid leukemia
por: Gu, Runxia, et al.
Publicado: (2017)

Effect of serum albumin level on high-dose methotrexate induced toxicities in acute lymphoblastic leukemia patients
por: Mirza, Mehdi Ali, et al.
Publicado: (2023)

Intracranial Hemorrhage Following Oral Low-Dose Methotrexate After Multiple Toxicities Caused by High-Dose Methotrexate in Childhood Acute Lymphoblastic Leukemia
por: Xin, Ning, et al.
Publicado: (2019)

High-Dose Methotrexate-Induced Idiopathic Intracranial Hypertension in Infant Acute Lymphoblastic Leukemia
por: Zhang, Yazhi, et al.
Publicado: (2020)

Case report: Intravitreal methotrexate in intraocular acute lymphoblastic leukemia
por: Pederzolli, Matteo, et al.
Publicado: (2022)

Methotrexate-Mediated Arachnoiditis in a Child with Acute Lymphoblastic Leukemia
por: Karamercan, Sırma, et al.
Publicado: (2022)

Intravitreal methotrexate in type B lymphoblastic leukemia—Case Report
por: Maya Naranjo, Maria Isabel, et al.
Publicado: (2023)

A novel variant translocation (1;9)(p22;q34) resulting in a DEK/NUP214 fusion gene in a patient with acute myeloid leukemia: A case report
por: Hao, Qishan, et al.
Publicado: (2017)

High-dose methotrexate vs. Capizzi methotrexate for the treatment of childhood T-cell acute lymphoblastic leukemia
por: Jastaniah, Wasil, et al.
Publicado: (2018)

Impact of genetic polymorphisms on chemotherapy toxicity in childhood acute lymphoblastic leukemia
por: Gervasini, Guillermo, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_coinab7j7c3cnbgvpm4r58pd8v