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Multienzyme deep learning models improve peptide de novo sequencing by mass spectrometry proteomics

Generating and analyzing overlapping peptides through multienzymatic digestion is an efficient procedure for de novo protein using from bottom-up mass spectrometry (MS). Despite improved instrumentation and software, de novo MS data analysis remains challenging. In recent years, deep learning models...

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Detalles Bibliográficos
Autores principales: Gueto-Tettay, Carlos, Tang, Di, Happonen, Lotta, Heusel, Moritz, Khakzad, Hamed, Malmström, Johan, Malmström, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891523/
https://www.ncbi.nlm.nih.gov/pubmed/36668672
http://dx.doi.org/10.1371/journal.pcbi.1010457